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Disse fremstilles ved industriell behandling av ekstrakter fra valmue eller kjemisk produksjon uavhengig av opiumråstoff, for eksempel oksykodon og fentanyl.მტკიცებულებებზე დაფუძნებული მედიცინა ცდილობს ობიექტურად შეაფასოს კლი
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